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씤꽣耳뼱뿉꽌 痍④툒븯뒗 媛 遺꾩빞 蹂 썝猷뚮 븞궡빐 뱶由쎈땲떎.
BEAUACTIVE
- Introduction
젣議곗썝 DSM
INCI Name Hydroxystearic Acid
븳湲 쟾꽦遺 븯씠뱶濡앹떆뒪뀒븘由븷뵪뱶
궗슜냽룄 0.1-1%
Activity 빆끂솕, 誘몃갚, 紐④났 媛먯냼
썝猷뚰듅꽦 (Story)
  • DSM궗쓽 깮臾 쟾솚 湲곗닠濡 媛쒕컻븳 紐④났怨 湲곕몃 빐寃고븯뒗 怨좎닚룄 슚뒫 븸떚釉(꽭룷蹂댄샇, 湲곕몄뼲젣, 끂솕濡 씤븳 紐④났媛먯냼 꽭媛吏 뵾遺怨좊 빐寃) 泥쒖뿰쑀옒 怨좎닚룄 쑀슜꽦 븸떚釉 꽦遺꾩씤 10-hydroxystearic acid뒗 諛쒗슚씤궪씠굹 씪蹂몄쓽 늻移대룄肄(諛쒗슚寃⑥젅엫)뿉룄 留롮씠 뱾뼱 엳뒗 꽦遺 UV뒪듃젅뒪 留덉빱 P53 뼲젣 諛 肄쒕씪寃 I, III 빀꽦 珥됱쭊 꽭룷瑜 議곗젅븯뒗 留덉뒪꽣 議곗젅옄씤 PPAR慣瑜 뿬뒗 뿴뇿 뿭븷쓣 븯뒗 꽦遺(in-silico model) 젅떚怨 鍮꾧탳뜲씠꽣 蹂댁쑀 (젅떚蹂대떎 肄쒕씪寃 III빀꽦 珥됱쭊 슚怨 슦닔)
슚뒫/슚怨 (硫붿빱땲利)
  • UV濡 씤븳 MMP-1 뼲젣, 솕긽꽭룷 媛먯냼(49%넃), 꽭룷 넀긽쓽 留덉빱씤 p53 諛쒗쁽 뼲젣(46%넃) 젅떚怨 肄쒕씪寃 III 빀꽦 珥됱쭊 鍮꾧탳(Beauactive媛 뜑 슦닔, ex-vivo) 1% Beauactive븿쑀 젣뭹쓣 븯猷 2쉶 궗슜븳 떎뿕援(38-65꽭)뿉꽌 湲곕몄 紐④났 궗씠利덇 솗뿰엳 媛먯냼
湲고
  • 以묎뎅 닔異 媛뒫, EWG 1벑湲, 듅뿀 異쒖썝以, SCI 끉臾. 80꼦뿉꽌 쑀긽 슜빐